Ezri Konsa, Rico Lewis and Cole Palmer have received maiden call-ups after Lewis Dunk, James Maddison and Callum Wilson withdrew from the England squad due to injuries.
Brighton’s Lewis Dunk has withdrawn from the squad with an adductor injury, which has led Aston Villa’s Konsa to receive his first call-up after previously winning the 2017 FIFA Under-20s World Cup with England.
Tottenham’s James Maddison meanwhile has been ruled out with an ankle injury suffered during their controversial loss at home to Chelsea, with Palmer named as his replacement after scoring four goals in the Blues’ last five matches – albeit from the penalty spot.
Callum Wilson is sidelined up front with a hamstring injury suffered during Newcastle’s Champions League loss at Borussia Dortmund, but manager – Gareth Southgate has opted not to directly replace him in attack.
Manchester City defender, Rico Lewis has instead been called up in place of Wilson as Southgate instead looked to bolster his defensive options.
England kick off their final pair of qualifiers with a home clash against Malta on Friday 17 November in a 7:45pm GMT kick-off at Wembley Stadium, London, before visiting North Macedonia on Monday 20 November in a 8:45pm CET (7:45pm UK Time) kick-off in Skopje.
Here is the 25-man England squad to face Malta and North Macedonia in full.
Goalkeepers: Sam Johnstone (Crystal Palace), Jordan Pickford (Everton), Aaron Ramsdale (Arsenal)
Defence: Levi Colwill (Chelsea), Marc Guehi (Crystal Palace), Ezri Konsa (Aston Villa), Rico Lewis (Manchester City), Harry Maguire (Manchester United), Fikayo Tomori (AC Milan), Kieran Trippier (Newcastle United), Kyle Walker (Manchester City)
Midfield: Trent Alexander-Arnold (Liverpool), Jude Bellingham (Real Madrid), Conor Gallagher (Chelsea), Jordan Henderson (Al-Ettifaq), Cole Palmer (Chelsea), Kalvin Phillips (Manchester City), Declan Rice (Arsenal)
Forward: Jarrod Bowen (West Ham), Phil Foden (Manchester City), Jack Grealish (Manchester City), Harry Kane (Bayern Munich), Marcus Rashford (Manchester United), Bukayo Saka (Arsenal), Ollie Watkins (Aston Villa)